Assay Detail
Functional
CHEMBL5247261
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Antiviral activity against Influenza A virus A/PR/8/34 (PR8) strain infected in MDCK cells assessed as reduction in viral infection incubated for 72 hrs by crystal violet staining based assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioisosteres of the Phenyl Ring: Recent Strategic Applications in Lead Optimization and Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.41 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2040554 | — | — | 1 | 6.48 |
| CHEMBL5286364 | — | — | 1 | 5.96 |
| CHEMBL467389 | — | — | 1 | 4.67 |
| CHEMBL2040641 | — | — | 1 | 4.53 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2040554 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL5286364 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL467389 | — | IC50 | = | 21300.0 | nM | 4.67 |
| CHEMBL2040641 | — | IC50 | = | 29400.0 | nM | 4.53 |