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Assay Detail

CHEMBL5250709

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to Shh (unknown origin) assessed as dissociation constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Sonic hedgehog protein (CHEMBL5602)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Current approaches and strategies to identify Hedgehog signaling pathway inhibitors for cancer therapy.
Feng Z, Zhu S, Li W, Yao M, Song H, Wang RB.
Eur J Med Chem (2022) 244 : 114867 -114867
PubMed 36332550 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.77 6.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5276737 1 6.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5276737 Kd = 170.0 nM 6.77