Assay Detail
Functional
CHEMBL5252148
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Antiparasitic activity against Cryptosporidium parvum assessed as parasitic growth inhibition measured for 24 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cryptosporidium parvum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure-activity relationship of BMS906024 derivatives for Cryptosporidium parvum growth inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.29 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5287227 | — | — | 1 | 5.60 |
| CHEMBL520733 | SEMAGACESTAT | 3.0 | 1 | 5.38 |
| CHEMBL255682 | — | — | 1 | 4.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5287227 | — | EC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL520733 | SEMAGACESTAT | EC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL255682 | — | EC50 | = | 12500.0 | nM | 4.90 |