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Target Snapshot

CHEMBL612855 Target Snapshot

Cryptosporidium parvum · ORGANISM · Cryptosporidium parvum

Back to Search Search this target Browse approvals Evidence Card
1,035Compounds
101Assays
8Approved Drugs
654.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Cryptosporidium parvum as ChEMBL target CHEMBL612855. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Cryptosporidium parvum
ORGANISM · Cryptosporidium parvum
As of 2026-09-14
ChEMBL target ID
CHEMBL612855
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Cryptosporidium parvum still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameCryptosporidium parvum
Target TypeORGANISM
OrganismCryptosporidium parvum
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelCryptosporidium parvum
UniProt AccessionN/A

Cryptosporidium parvum

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Cryptosporidium parvum.

Review nameCryptosporidium parvum
OrganismCryptosporidium parvum
Clinical Profile

Clinical Phase Distribution

8
Approved
1
Phase III
2
Phase II
Assay Mix

Activity Type Distribution

IC50382.0
EC50272.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4297269 8.74 EC50 1.8 Clinical
CHEMBL917 8.3 EC50 5.0 Approved
CHEMBL5277661 8.19 EC50 6.4 Preclinical
CHEMBL5290152 7.75 EC50 18.0 Preclinical
CHEMBL5269363 7.6 EC50 25.0 Preclinical
CHEMBL76 7.57 IC50 27.0 Approved
CHEMBL5268899 7.51 EC50 31.0 Preclinical
CHEMBL2078876 7.3 IC50 50.0 Preclinical
CHEMBL3109011 7.3 IC50 50.0 Preclinical
CHEMBL5280057 7.28 EC50 52.0 Preclinical
Distribution

pChEMBL Value Distribution

30
5.0
52
5.5
67
6.0
21
6.5
10
7.0
4
7.5
3
8.0
2
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

PYRVINIUM
CHEMBL1201303
Approved 1982
Properties Compare Identifier
FLOXURIDINE
CHEMBL917
Approved 1970
Properties Compare Identifier
PAROMOMYCIN
CHEMBL370143
Approved 1969
Properties Compare Identifier
CHLOROQUINE
CHEMBL76
Approved 1949
Properties Compare Identifier
Assay Landscape

Assay Landscape

101
Total Assays
281
Tested Compounds
1
Assay Types
Functional — 101 assays, 281 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 101 281 5.6

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine