Assay Detail
Binding
CHEMBL5253510
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human AChE assessed as hydrolysis of acetylthiocholine by Ellman's method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Biological importance of structurally diversified chromenes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.82 | 7.98 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL244416 | — | — | 1 | 7.98 |
| CHEMBL396247 | — | — | 1 | 7.98 |
| CHEMBL396199 | — | — | 1 | 7.98 |
| CHEMBL75121 | — | — | 1 | 7.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL244416 | — | Ki | = | 10.5 | nM | 7.98 |
| CHEMBL396247 | — | Ki | = | 10.5 | nM | 7.98 |
| CHEMBL396199 | — | Ki | = | 10.5 | nM | 7.98 |
| CHEMBL75121 | — | Ki | = | 44.5 | nM | 7.35 |