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Assay Detail

CHEMBL5255503

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Rift Valley fever virus MP-12 infected in African green monkey Vero 76 cells by visual analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rift Valley fever virus
Cell Type Vero 76
Confidence 1 — Organism
Curated By Autocuration

Target

Rift Valley fever virus (CHEMBL613130)
Type ORGANISM
Organism Rift Valley fever virus

Publication

2- and 3-Fluoro-3-deaza-1',6'-isoneplanocin: Synthesis and antiviral properties (including Ebola and Marburg).
Liu C, Chen Q, Schneller SW.
Bioorg Med Chem Lett (2023) 85 : 129219 -129219
PubMed 36898483 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 4.49 4.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5275097 1 4.66
CHEMBL1643 RIBAVIRIN 4.0 1 4.31

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5275097 EC50 = 22100.0 nM 4.66
CHEMBL1643 RIBAVIRIN EC50 = 49000.0 nM 4.31