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Assay Detail

CHEMBL5257290

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antibiofilm activity against Pseudomonas aeruginosa assessed as reduction in biofilm formation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Pseudomonas aeruginosa
Confidence 1 — Organism
Curated By Autocuration

Target

Pseudomonas aeruginosa (CHEMBL348)
Type ORGANISM
Organism Pseudomonas aeruginosa

Publication

Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections.
Wagner S, Sommer R, Hinsberger S, Lu C, Hartmann RW, Empting M, Titz A.
J Med Chem (2016) 59 : 5929 -5969
PubMed 26804741 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.96 7.34

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2018916 1 7.34
CHEMBL1733252 1 4.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2018916 IC50 = 46.0 nM 7.34
CHEMBL1733252 IC50 = 26000.0 nM 4.58