Compound Detail
CHEMBL1733252
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Basic Information
| ChEMBL ID | CHEMBL1733252 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GIXMMHJWAHQSSW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
288.4
MW (Da)
4.68
ALogP
2
HBA
2
HBD
41.1
PSA (Ų)
0.73
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.58
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Pseudomonas aeruginosa CHEMBL348 | IC50 | 4.58 | 4.58 | 26000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Pseudomonas aeruginosa | IC50 | = | 26000.0 | nM | 4.58 | Antibiofilm activity against Pseudomonas aeruginosa assessed as reduction in bio... | 26804741 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26804741 | 10.1021/acs.jmedchem.5b01698 | Pseudomonas aeruginosa | 2 |
Data from ChEMBL 36 via Core Engine