Assay Detail
Functional
CHEMBL5257804
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV-1 infected in CEM-SS cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | CEM-SS |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Therapeutic potential of coumarins as antiviral agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.44 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267447 | CALANOLIDE A | 1.0 | 1 | 7.00 |
| CHEMBL7121 | (+)-CALANOLIDE B | — | 1 | 6.40 |
| CHEMBL269090 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267447 | CALANOLIDE A | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL7121 | (+)-CALANOLIDE B | EC50 | = | 400.0 | nM | 6.40 |
| CHEMBL269090 | — | EC50 | = | 1200.0 | nM | 5.92 |