Assay Detail
Binding
CHEMBL5258029
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Binding affinity to angiotensin-converting enzyme (unknown origin) assessed as inhibition constant
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Side Chain Cyclized Aromatic Amino Acids: Great Tools as Local Constraints in Peptide and Peptidomimetic Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.97 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5281720 | — | — | 1 | 8.70 |
| CHEMBL5279614 | — | — | 1 | 8.00 |
| CHEMBL298827 | (S)-THIORPHAN | — | 1 | 6.89 |
| CHEMBL5266415 | — | — | 1 | 4.30 |
| CHEMBL5272537 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5281720 | — | Ki | = | 2.0 | nM | 8.70 |
| CHEMBL5279614 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL298827 | (S)-THIORPHAN | Ki | = | 130.0 | nM | 6.89 |
| CHEMBL5266415 | — | Ki | = | 50000.0 | nM | 4.30 |
| CHEMBL5272537 | — | Ki | = | 0.004 | nM | - |