Assay Detail
Binding
CHEMBL5258581
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human IBAT
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Ileal sodium/bile acid cotransporter (CHEMBL2778) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Trust Your Gut: Strategies and Tactics for Intestinally Restricted Drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.55 | 9.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL363392 | MARALIXIBAT | 4.0 | 1 | 9.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL363392 | MARALIXIBAT | IC50 | = | 0.28 | nM | 9.55 |