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Assay Detail

CHEMBL5259013

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Staphylococcus aureus FTsZ GTPase activity
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Staphylococcus aureus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cell division protein FtsZ (CHEMBL5096)
Type SINGLE PROTEIN
Organism Staphylococcus aureus

Publication

Bacterial GTPases as druggable targets to tackle antimicrobial resistance.
Shanbhag C, Saraogi I.
Bioorg Med Chem Lett (2023) 87 : 129276 -129276
PubMed 37030567 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.82 6.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL511201 1 6.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL511201 IC50 = 150.0 nM 6.82