Assay Detail
Functional
CHEMBL5259526
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against MERS-CoV infected in vervet monkey MA-104 cells assessed as reduction in virus-induced cytopathic effect measured after 15 to 30 mins by neutral red dye based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Middle East respiratory syndrome-related coronavirus |
| Cell Type | MA-104 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Middle East respiratory syndrome-related coronavirus (CHEMBL4296578) ↗| Type | ORGANISM |
| Organism | Middle East respiratory syndrome-related coronavirus |
Publication
An Isomer of Galidesivir That Potently Inhibits Influenza Viruses and Members of the <i>Bunyavirales</i> Order.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.72 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5270241 | — | — | 1 | 5.00 |
| CHEMBL1236524 | GALIDESIVIR | 2.0 | 1 | 4.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5270241 | — | EC50 | = | 9900.0 | nM | 5.00 |
| CHEMBL1236524 | GALIDESIVIR | EC50 | = | 36000.0 | nM | 4.44 |