Assay Detail
Functional
CHEMBL5260125
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Vasorelaxant activity in rat endothelium-intact rat main mesenteric artery assessed as increased sensitivity in tissues
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Mesenteric artery |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of 6-alkoxy and 6-hydroxy-alkyl amine derivatives of braylin as vasorelaxing agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.80 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL529210 | — | — | 1 | 5.80 |
| CHEMBL71851 | SCOPOLETIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL529210 | — | EC50 | = | 1580.0 | nM | 5.80 |
| CHEMBL71851 | SCOPOLETIN | EC50 | = | 112000.0 | nM | - |