Assay Detail
Binding
CHEMBL5260671
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PI5P4Kalpha (unknown origin) incubated for 1 hr in presence of [33P]gamma-ATP and ATP by fluorescence based analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (CHEMBL1795194) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification of ARUK2002821 as an isoform-selective PI5P4Kα inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.40 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5271804 | — | — | 1 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5271804 | — | IC50 | = | 40.0 | nM | 7.40 |