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Assay Detail

CHEMBL5260871

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant human GSTA1-1
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Glutathione S-transferase A1 (CHEMBL3409)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Benzophenone: a ubiquitous scaffold in medicinal chemistry.
Surana K, Chaudhary B, Diwaker M, Sharma S.
Medchemcomm (2018) 9 : 1803 -1817
PubMed 30542530 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 6.75 6.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3310888 1 6.75
CHEMBL3310886 1 6.75
CHEMBL3310887 1 6.75
CHEMBL5289853 1 6.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3310888 IC50 = 180.0 nM 6.75
CHEMBL3310886 IC50 = 180.0 nM 6.75
CHEMBL3310887 IC50 = 180.0 nM 6.75
CHEMBL5289853 IC50 = 180.0 nM 6.75