Assay Detail
Functional
CHEMBL5261583
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Antibacterial activity against Escherichia coli
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Escherichia coli |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Isoxazole ring as a useful scaffold in a search for new therapeutic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.18 | 5.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL185719 | — | — | 1 | 5.36 |
| CHEMBL184732 | — | — | 1 | 5.19 |
| CHEMBL186355 | — | — | 1 | 5.16 |
| CHEMBL364597 | — | — | 1 | 5.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL185719 | — | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL184732 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL186355 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL364597 | — | IC50 | = | 9800.0 | nM | 5.01 |