Assay Detail
Binding
CHEMBL5262369
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human partial length BRDT bromodomain 2 (K250 to E382 residues) expressed in bacterial expression system by BROMOscan assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Bromodomain testis-specific protein (CHEMBL1795185) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 5.41 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5282240 | — | — | 1 | 5.58 |
| CHEMBL5270178 | — | — | 1 | 5.46 |
| CHEMBL5289762 | — | — | 1 | 5.18 |
| CHEMBL5268484 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5282240 | — | Kd | = | 2600.0 | nM | 5.58 |
| CHEMBL5270178 | — | Kd | = | 3500.0 | nM | 5.46 |
| CHEMBL5289762 | — | Kd | = | 6600.0 | nM | 5.18 |
| CHEMBL5268484 | — | Kd | > | 10000.0 | nM | - |