Use UniProt Q58F21 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1795185 Target Snapshot
Bromodomain testis-specific protein · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q58F21. Use UniProt Q58F21 as the stable identity anchor, then attach disease evidence before program review.
Bromodomain testis-specific protein
Review this target as Bromodomain testis-specific protein, mapped to UniProt Q58F21. Sequence length is 947 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Bromodomain testis-specific protein as ChEMBL target CHEMBL1795185, mapped to UniProt Q58F21. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Bromodomain testis-specific protein |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q58F21 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Bromodomain testis-specific protein |
| UniProt Accession | Q58F21 |
| Component Type | Protein |
| Sequence Length | 947 aa |
Bromodomain testis-specific protein
How to read this target
Review this target as Bromodomain testis-specific protein, mapped to UniProt Q58F21. Sequence length is 947 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5170488 | 10.24 | Kd | 0.058 | Preclinical |
| CHEMBL4648912 | 9.85 | Kd | 0.14 | Preclinical |
| CHEMBL5188470 | 9.8 | Kd | 0.16 | Preclinical |
| CHEMBL5201173 | 9.23 | Kd | 0.59 | Preclinical |
| CHEMBL5204093 | 9.22 | Kd | 0.6 | Preclinical |
| CHEMBL5206426 | 9.22 | Kd | 0.6 | Preclinical |
| CHEMBL4208129 | 9.16 | Ki | 0.69 | Preclinical |
| CHEMBL5178175 | 9.04 | Kd | 0.92 | Preclinical |
| CHEMBL4297454 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL4869149 | 8.8 | IC50 | 1.585 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 283 assays, 287 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 173 | 184 | 6.4 |
| assay format | 93 | 81 | 6.7 |
| cell-based format | 15 | 21 | 6.7 |
| subcellular format | 2 | 1 | 8.0 |
Functional — 14 assays, 3 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 12 | 2 | 6.9 |
| tissue-based format | 2 | 1 | 5.9 |
ADME — 4 assays, 3 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 2 | 5.7 |
| assay format | 1 | 1 | 4.6 |