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Assay Detail

CHEMBL5263040

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anticancer activity against human HL-60 cells assessed as cell growth inhibition by trypan blue staining based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HL-60
Confidence 1 — Organism
Curated By Autocuration

Target

HL-60 (CHEMBL383)
Type CELL-LINE
Organism Homo sapiens

Publication

Polyamine-based analogs and conjugates as antikinetoplastid agents.
Jagu E, Pomel S, Pethe S, Loiseau PM, Labruère R.
Eur J Med Chem (2017) 139 : 982 -1015
PubMed 28886510 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL227559 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL227559 IC50 = 1000.0 nM 6.00