Assay Detail
Functional
CHEMBL5263053
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiprotozoal activity against Trypanosoma brucei rhodesiense
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei rhodesiense |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Trypanosoma brucei rhodesiense (CHEMBL612348) ↗| Type | ORGANISM |
| Organism | Trypanosoma brucei rhodesiense |
Publication
Polyamine-based analogs and conjugates as antikinetoplastid agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.96 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL41629 | — | — | 1 | 6.80 |
| CHEMBL311566 | — | — | 1 | 6.01 |
| CHEMBL5274097 | — | — | 1 | 5.81 |
| CHEMBL2314239 | — | — | 1 | 5.23 |
| CHEMBL1789344 | — | — | 1 | - |
| CHEMBL1789813 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL41629 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL311566 | — | IC50 | = | 980.0 | nM | 6.01 |
| CHEMBL5274097 | — | IC50 | = | 1560.0 | nM | 5.81 |
| CHEMBL2314239 | — | IC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL1789344 | — | IC50 | > | 40000.0 | nM | - |
| CHEMBL1789813 | — | IC50 | > | 40000.0 | nM | - |