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Assay Detail

CHEMBL5263086

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiprotozoal activity against Leishmania mexicana infected in mouse J774 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Leishmania mexicana
Cell Type J774
Confidence 1 — Organism
Curated By Autocuration

Target

Leishmania mexicana (CHEMBL612880)
Type ORGANISM
Organism Leishmania mexicana

Publication

Polyamine-based analogs and conjugates as antikinetoplastid agents.
Jagu E, Pomel S, Pethe S, Loiseau PM, Labruère R.
Eur J Med Chem (2017) 139 : 982 -1015
PubMed 28886510 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL561057 SQ109 2.0 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL561057 SQ109 IC50 = 10.0 nM 8.00