Assay Detail
Functional
CHEMBL5263114
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Antiprotozoal activity against Trypanosoma brucei brucei Lab 110 EATRO strain
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei brucei |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Polyamine-based analogs and conjugates as antikinetoplastid agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.90 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL269032 | — | — | 1 | 8.70 |
| CHEMBL534529 | — | — | 1 | 7.75 |
| CHEMBL9126 | — | — | 1 | 7.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL269032 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL534529 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL9126 | — | IC50 | = | 58.0 | nM | 7.24 |