Assay Detail
Binding
CHEMBL5263444
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human liver FBPase expressed in Escherichia coli by spectrophotometry method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Tissue | Liver |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Fructose-1,6-bisphosphatase inhibitors: A new valid approach for management of type 2 diabetes mellitus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.99 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL752 | ADENOSINE PHOSPHATE | 4.0 | 1 | 6.00 |
| CHEMBL483849 | — | — | 1 | 4.92 |
| CHEMBL570790 | — | — | 1 | 4.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL752 | ADENOSINE PHOSPHATE | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL483849 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL570790 | — | IC50 | = | 90000.0 | nM | 4.05 |