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Assay Detail

CHEMBL5263733

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against mouse NIH3T3 cells expressing TRP/Met protein assessed as reduction in cell proliferation incubated for 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type NIH3T3
Confidence 1 — Organism
Curated By Autocuration

Target

NIH3T3 (CHEMBL614822)
Type CELL-LINE
Organism Mus musculus

Publication

Recent advances in the discovery of small molecule c-Met Kinase inhibitors.
Parikh PK, Ghate MD.
Eur J Med Chem (2018) 143 : 1103 -1138
PubMed 29157685 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.80 5.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5287421 1 5.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5287421 IC50 = 1600.0 nM 5.80