Assay Detail
Functional
CHEMBL5263945
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Hepatoprotective activity against D-GaIN/TNFalpha -induced cell death in mouse hepatocyte assessed as inhibition of cell death
7
Total Activities
7
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Hepatocyte |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hepatoprotective natural triterpenoids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 5 | - | - |
| IC50 | 2 | 4.25 | 4.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5284510 | — | — | 1 | 4.29 |
| CHEMBL515706 | — | — | 1 | 4.21 |
| CHEMBL5289820 | — | — | 1 | - |
| CHEMBL5285799 | — | — | 1 | - |
| CHEMBL5288461 | — | — | 1 | - |
| CHEMBL5278543 | — | — | 1 | - |
| CHEMBL5285421 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5284510 | — | IC50 | = | 51200.0 | nM | 4.29 |
| CHEMBL515706 | — | IC50 | = | 60900.0 | nM | 4.21 |
| CHEMBL5289820 | — | Activity | = | 37.6 | % | - |
| CHEMBL5285799 | — | Activity | = | 37.6 | % | - |
| CHEMBL5288461 | — | Activity | = | 37.6 | % | - |
| CHEMBL5278543 | — | Activity | = | 37.6 | % | - |
| CHEMBL5285421 | — | Activity | = | 37.6 | % | - |