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Assay Detail

CHEMBL5263987

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HCV RNA IRES IIa by FRET assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Hepacivirus hominis
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

An overview of quinazolines: Pharmacological significance and recent developments.
Alagarsamy V, Chitra K, Saravanan G, Solomon VR, Sulthana MT, Narendhar B.
Eur J Med Chem (2018) 151 : 628 -685
PubMed 29656203 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 4.00 4.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5291148 1 4.00
CHEMBL1196896 1 -
CHEMBL5272910 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5291148 EC50 = 100000.0 nM 4.00
CHEMBL1196896 EC50 = 420000.0 nM -
CHEMBL5272910 EC50 = 650000.0 nM -