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Assay Detail

CHEMBL5265485

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human LNCaP cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type LNCaP
Confidence 1 — Organism
Curated By Autocuration

Target

LNCaP (CHEMBL612518)
Type CELL-LINE
Organism Homo sapiens

Publication

Small Molecules Targeting Activated Cdc42-Associated Kinase 1 (ACK1/TNK2) for the Treatment of Cancers.
Wang A, Pei J, Shuai W, Lin C, Feng L, Wang Y, Lin F, Ouyang L, Wang G.
J Med Chem (2021) 64 : 16328 -16348
PubMed 34735773 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.16 5.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL247070 1 5.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL247070 IC50 = 7000.0 nM 5.16