Assay Detail
Functional
CHEMBL5304366
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cellular PDE9A assay
2
Total Activities
2
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (CHEMBL5169102) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Data for DCP probe BAY-7081
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.00 | 6.00 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Assay publication | Assay publication | - | — | PMID: 36475653 |
| Target protein type | Target protein type | - | — | recombinant CHO cell line stably expressing murine PDE9A |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5306577 | — | — | 1 | 6.00 |
| CHEMBL5308250 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5306577 | — | EC50 | = | 995.0 | nM | 6.00 |
| CHEMBL5308250 | — | EC50 | > | 10000.0 | nM | - |