Assay Detail
Toxicity
CHEMBL5317221
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Cytotoxicity against human Bone marrow cell assessed as reduction in cell viability measured after 7 days
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Homo sapiens |
| Cell Type | Bone marrow cell |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.66 | 7.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5397585 | — | — | 1 | 7.66 |
| CHEMBL5411016 | — | — | 1 | - |
| CHEMBL5434894 | — | — | 1 | - |
| CHEMBL5428051 | — | — | 1 | - |
| CHEMBL5439842 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5397585 | — | IC50 | = | 22.0 | nM | 7.66 |
| CHEMBL5411016 | — | IC50 | > | 100.0 | nM | - |
| CHEMBL5434894 | — | IC50 | > | 50.0 | nM | - |
| CHEMBL5428051 | — | IC50 | > | 50.0 | nM | - |
| CHEMBL5439842 | — | IC50 | > | 50.0 | nM | - |