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Assay Detail

CHEMBL5317878

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of alpha amylase (unknown origin) measured after 20 to 25 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Alpha amylase (CHEMBL6066863)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Mechanistic Insight of Synthesized 1,4-Dihydropyridines as an Antidiabetic Sword against Reactive Oxygen Species.
Sidhom PA, El-Bastawissy E, Ibrahim MAA, Shawky AM, Salama A, El-Moselhy T.
J Med Chem (2023) 66 : 991 -1010
PubMed 36584305 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.93 5.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL50 QUERCETIN 3.0 1 5.09
CHEMBL5414025 1 4.76

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL50 QUERCETIN IC50 = 8210.0 nM 5.09
CHEMBL5414025 IC50 = 17320.0 nM 4.76