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Assay Detail

CHEMBL5318490

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against monkey LLC-MK2 cells assessed as reduction in cell viability
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Macaca mulatta
Cell Type LLC-MK2
Confidence 1 — Organism
Curated By Autocuration

Target

LLC-MK2 (CHEMBL614691)
Type CELL-LINE
Organism Macaca mulatta

Publication

Novel Diarylthioether Compounds as Agents for the Treatment of Chagas Disease.
Beveridge J, Tran E, Deora GS, Huang F, Wang Y, Stockton K, Cotillo I, Martinez Martinez MS, Gonzalez S, Castañeda P, Sherman J, Rodriguez A, Kessler A, Baell JB.
J Med Chem (2023) 66 : 1522 -1542
PubMed 36626662 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.35 6.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3431410 1 6.35

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3431410 IC50 = 446.68 nM 6.35