Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5318993

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of FLT4 (unknown origin) by kinase profiling assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Vascular endothelial growth factor receptor 3 (CHEMBL1955)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of Novel Indazole Chemotypes as Isoform-Selective JNK3 Inhibitors for the Treatment of Parkinson's Disease.
Shuai W, Bu F, Zhu Y, Wu Y, Xiao H, Pan X, Zhang J, Sun Q, Wang G, Ouyang L.
J Med Chem (2023) 66 : 1273 -1300
PubMed 36649216 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.37 6.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5393904 1 6.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5393904 IC50 = 423.2 nM 6.37