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Assay Detail

CHEMBL5320877

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of yeast alpha-glucosidase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Saccharomyces cerevisiae
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Alpha-glucosidase (CHEMBL5291954)
Type PROTEIN FAMILY
Organism Saccharomyces cerevisiae S288c

Publication

Synthesis of the Purported Structure of Glyphaeaside C and Proposed Revisions to the Structures of the Glyphaeaside Alkaloids.
Byatt BJ, Kato A, Pyne SG.
J Nat Prod (2023) 86 : 1261 -1273
PubMed 37125736 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.09 4.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2177695 1 4.15
CHEMBL5429566 1 4.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2177695 IC50 = 71000.0 nM 4.15
CHEMBL5429566 IC50 = 95000.0 nM 4.02