Assay Detail
Binding
CHEMBL5323331
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Binding affinity to Escherichia coli ribosomes assessed as apparent inhibition constant by scintillation counter analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Subcellular | Ribosome |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A method for tritiation of iboxamycin permits measurement of its ribosomal binding.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.48 | 7.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5428248 | — | — | 1 | 7.39 |
| CHEMBL1753 | CLINDAMYCIN | 4.0 | 1 | 5.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5428248 | — | Ki | = | 41.0 | nM | 7.39 |
| CHEMBL1753 | CLINDAMYCIN | Ki | = | 2700.0 | nM | 5.57 |