Assay Detail
Functional
CHEMBL5324945
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at 5-HT2B receptor (unknown origin) by calcium flux assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.85 | 9.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5419724 | — | — | 1 | 9.43 |
| CHEMBL5400876 | — | — | 1 | 6.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5419724 | — | IC50 | = | 0.37 | nM | 9.43 |
| CHEMBL5400876 | — | IC50 | = | 532.0 | nM | 6.27 |