Assay Detail
Toxicity
CHEMBL5326414
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human Cathepsin L using Cbz-Phe-Arg-AMC as substrate by fluorescence spectrophotometric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Falcipains: Biochemistry, target validation and structure-activity relationship studies of inhibitors as antimalarials.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.34 | 6.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3218476 | — | — | 1 | 6.09 |
| CHEMBL200151 | — | — | 1 | 4.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3218476 | — | Ki | = | 820.0 | nM | 6.09 |
| CHEMBL200151 | — | Ki | = | 26500.0 | nM | 4.58 |