Assay Detail
Binding
CHEMBL5328116
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human Pin1 using Suc-AEPF-NH-Np as substrate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (CHEMBL2288) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Biological Function of Pin1 in Vivo and Its Inhibitors for Preclinical Study: Early Development, Current Strategies, and Future Directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.30 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL43612 | JUGLONE | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL43612 | JUGLONE | IC50 | = | 5000.0 | nM | 5.30 |