Assay Detail
Functional
CHEMBL5328532
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Antiproliferative activity against human RS4-11 cells assessed as cell growth inhibition incubated for 48 hrs by CCK8 colorimetric assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | RS4-11 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Facilitated Drug Repurposing with Artemisinin-Derived PROTACs: Unveiling PCLAF as a Therapeutic Target.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.89 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5439922 | — | — | 1 | 7.30 |
| CHEMBL5404231 | — | — | 1 | 7.14 |
| CHEMBL5401559 | — | — | 1 | 7.10 |
| CHEMBL5412264 | — | — | 1 | 7.01 |
| CHEMBL5431842 | — | — | 1 | 6.62 |
| CHEMBL4856977 | — | — | 1 | 6.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5439922 | — | IC50 | = | 50.6 | nM | 7.30 |
| CHEMBL5404231 | — | IC50 | = | 72.4 | nM | 7.14 |
| CHEMBL5401559 | — | IC50 | = | 79.4 | nM | 7.10 |
| CHEMBL5412264 | — | IC50 | = | 96.8 | nM | 7.01 |
| CHEMBL5431842 | — | IC50 | = | 242.7 | nM | 6.62 |
| CHEMBL4856977 | — | IC50 | = | 640.6 | nM | 6.19 |