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Assay Detail

CHEMBL5329116

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against wild type HIV 1 NL4-3
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Confidence 1 — Organism
Curated By Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

Sub-stoichiometric Modulation of Viral Targets-Potent Antiviral Agents That Exploit Target Vulnerability.
Meanwell NA.
ACS Med Chem Lett (2023) 14 : 1021 -1030
PubMed 37583823 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 8.87 9.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4788357 1 9.22
CHEMBL4792897 1 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4788357 EC50 = 0.6 nM 9.22
CHEMBL4792897 EC50 = 3.0 nM 8.52