Assay Detail
Functional
CHEMBL5329119
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV 1 harbouring V362I/V370 mutant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Sub-stoichiometric Modulation of Viral Targets-Potent Antiviral Agents That Exploit Target Vulnerability.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 8.17 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5201510 | FIPRAVIRIMAT | 2.0 | 1 | 8.52 |
| CHEMBL4792897 | — | — | 1 | 7.82 |
| CHEMBL3827379 | BMS-955176 | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5201510 | FIPRAVIRIMAT | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL4792897 | — | EC50 | = | 15.0 | nM | 7.82 |
| CHEMBL3827379 | BMS-955176 | EC50 | > | 3000.0 | nM | - |