Assay Detail
Binding
CHEMBL5329426
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Inhibition of beta-hematin formation
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Is structural hybridization invoking new dimensions for antimalarial drug discovery research?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.49 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 6.75 |
| CHEMBL5394575 | — | — | 1 | 6.41 |
| CHEMBL5414513 | — | — | 1 | 6.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL5394575 | — | IC50 | = | 390.0 | nM | 6.41 |
| CHEMBL5414513 | — | IC50 | = | 480.0 | nM | 6.32 |