Assay Detail
Functional
CHEMBL5330218
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Antimycobacterial activity against Mycobacterium tuberculosis assessed as reduction in bacterial growth measured after 7 days by fluorescence microplate analysis
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mycobacterium tuberculosis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeting <i>Mycobacterium tuberculosis</i> iron-scavenging tools: a recent update on siderophores inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.94 | 6.07 |
| MIC | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1713178 | — | — | 1 | 6.07 |
| CHEMBL1336959 | — | — | 1 | 5.80 |
| CHEMBL5407107 | — | — | 1 | - |
| CHEMBL5422171 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1713178 | — | IC50 | = | 860.0 | nM | 6.07 |
| CHEMBL1336959 | — | IC50 | = | 1590.0 | nM | 5.80 |
| CHEMBL5407107 | — | MIC | = | 780.0 | nM | - |
| CHEMBL5422171 | — | MIC | = | 37000.0 | nM | - |