Assay Detail
Binding
CHEMBL5331160
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Binding affinity to mushroom tyrosinase assessed as inhibition constant
4
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Azole inhibitors of mushroom and human tyrosinases: Current advances and prospects of drug development for melanogenic dermatological disorders.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.88 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5430164 | — | — | 2 | 8.52 |
| CHEMBL5436607 | — | — | 2 | 8.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5430164 | — | Ki | = | 3.02 | nM | 8.52 |
| CHEMBL5436607 | — | Ki | = | 5.85 | nM | 8.23 |
| CHEMBL5430164 | — | Ki | = | 3020.0 | nM | 5.52 |
| CHEMBL5436607 | — | Ki | = | 5850.0 | nM | 5.23 |