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Assay Detail

CHEMBL5331209

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HL-60 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HL-60
Confidence 1 — Organism
Curated By Autocuration

Target

HL-60 (CHEMBL383)
Type CELL-LINE
Organism Homo sapiens

Publication

A comprehensive review on acridone based derivatives as future anti-cancer agents and their structure activity relationships.
Yadav TT, Murahari M, Peters GJ, Yc M.
Eur J Med Chem (2022) 239 : 114527 -114527
PubMed 35717872 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.35 6.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5416585 1 6.35

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5416585 IC50 = 450.0 nM 6.35