Assay Detail
Binding
CHEMBL5331256
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to NDM1 (unknown origin) assessed as inhibition constant by measuring imipenem hydrolysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacteria |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advances in β-lactamase inhibitor chemotypes and inhibition modes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.94 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4639950 | — | — | 1 | 5.16 |
| CHEMBL5267944 | — | — | 1 | 4.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4639950 | — | Ki | = | 7000.0 | nM | 5.16 |
| CHEMBL5267944 | — | Ki | = | 19000.0 | nM | 4.72 |