Assay Detail
Binding
CHEMBL5331293
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of NDM1 (unknown origin) using fluorescent cephalosporin FC5 as substrate incubated for 15 mins followed by substrate addition measured by fluorescence based analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacteria |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advances in β-lactamase inhibitor chemotypes and inhibition modes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.97 | 6.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5396533 | — | — | 1 | 6.04 |
| CHEMBL1234848 | NITRILOTRIACETIC ACID | — | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5396533 | — | IC50 | = | 910.0 | nM | 6.04 |
| CHEMBL1234848 | NITRILOTRIACETIC ACID | IC50 | = | 1300.0 | nM | 5.89 |