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Assay Detail

CHEMBL5331480

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Antagonist activity at human ETA receptor expressed in CHO cells assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Endothelin-1 receptor (CHEMBL252)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Recent progress toward developing axial chirality bioactive compounds.
Wang Z, Meng L, Liu X, Zhang L, Yu Z, Wu G.
Eur J Med Chem (2022) 243 : 114700 -114700
PubMed 36058089 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 11.00 11.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL274489 1 11.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL274489 Ki = 0.01 nM 11.00