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Assay Detail

CHEMBL5331483

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Functional
Anticancer activity against human HCT-116 cells assessed as cell growth inhibition
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HCT-116
Confidence 1 — Organism
Curated By Autocuration

Target

HCT-116 (CHEMBL394)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent progress toward developing axial chirality bioactive compounds.
Wang Z, Meng L, Liu X, Zhang L, Yu Z, Wu G.
Eur J Med Chem (2022) 243 : 114700 -114700
PubMed 36058089 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.06 5.06

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3393621 1 5.06
CHEMBL5399631 1 5.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3393621 IC50 = 8800.0 nM 5.06
CHEMBL5399631 IC50 = 9000.0 nM 5.05