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Assay Detail

CHEMBL5332008

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Neuroprotective activity in Wistar rat brain homogenate assessed as inhibition of lipid peroxidation incubated for 10 mins by fluorometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Tissue Brain
Confidence 1 — Organism
Curated By Autocuration

Target

Brain (CHEMBL613617)
Type TISSUE
Organism Rattus norvegicus

Publication

A decade of approved first-in-class small molecule orphan drugs: Achievements, challenges and perspectives.
Gu J, Wu Q, Zhang Q, You Q, Wang L.
Eur J Med Chem (2022) 243 : 114742 -114742
PubMed 36155354 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.74 4.74

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL290916 EDARAVONE 4.0 1 4.74

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL290916 EDARAVONE IC50 = 18200.0 nM 4.74